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Found 2 items.
HEMATOLOGICAL INDICATORS OF EXPERIMENTAL STUDY OF CHRONIC TOXICITY OF DOMESTIC PASTE-LIKE COMPOSITE
The emergence of osteoplastic materials and new methods of bone regeneration not only solve the problem of the volume and density of the jaw bones, but also significantly improve the results of implantation. The ami of the research is search and development of new domestic osteoplastic materials remains relevant. The results of acute toxicity detection allow us to classify the domestic pasty composite material as a group of practically non-toxic materials according to the International classification of material toxicity.
B Khabilov, A Akbarov, N Ziyadullaeva
10-12
2020-04-26
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COMPARATIVE EVALUATION OF NEW OSTEOPLASTIC RAW MATERIALS BASED ON THE RESULTS OF ACUTE VENOM RESEARCH
Comparative assessment of the degree of harmful effects on experimental animals of the new osteoplastic material 47.5B and domestic bioactive glass BG-1D and assessment of its safety for use as an osteoplastic material. Material and methods: Three series of experiments were earned out and lethal doses were determined for the intraperitoneal and intragastric routes of administration of the drug to laboratory animals. Results: LD50 47.5B was 4274.51:4770.58 mg/kg when administered intragastrically and 2358.31:2895.65 mg/kg when administered intraperitoneally to rats. In animals that received bioactive glass BG-1D, this indicator changed slightly, amounting to 3439.04:3810.53 and 1732.77:2730.93 mg/kg, respectively. Conclusions: These materials can be attributed to practically non-toxic substances (according to the results of intraperitoneal administration of a suspension of substances to rats and mice) and to low-toxic substances (according to the results of intragastric M administration of a suspension of substances to rats).
A Akbarov, N Ziyadullaeva, A Raxmanov, M Axmedov
8-10
2021-03-26
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1 - 2 of 2 items
“Stomatologiya” is a dental journal of the Republic of Uzbekistan, which has been published since 1998 and is the press organ of the Association of Dentists of Uzbekistan.
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